Monthly after IVF may be a predictable rate or pathological abnormality. The excitement of a woman is understandable, because usually, childless IVF couples have the only hope of creating a full-fledged family with children. In addition, we must not forget that the price of IVF is far from symbolic, and any deviation after the procedure, of course, is alarming.
The essence of in vitro fertilization procedure
The essence of IVF is the implantation of a fertilized egg in the uterus of a woman. At first glance, nothing complicated about it. But in fact, the engraftment of the egg occurs the first time in one of three cases. After all, all the processes in a woman's body are controlled by hormones, and any deviation from the norm will not allow her to become pregnant even with the help of IVF.
That is why a woman undergoes a long and complicated course of hormonal therapy before the procedure. Monthly after IVF should disappear, as well as in the case of pregnancy in a natural way. However, this is not an indicator of the conception occurred. It can be determined using the hormone hCG assay.
Bleeding after IVF
Monthly after IVF excluded, but possible slight bleeding. In the first days after the procedure, the woman is irritated, confused, and experiencing severe stress. All this is due to the hormonal background of the organism preparing for conception. It does not happen immediately. The egg cell does not fit directly into the uterus, it gets to it alone, as with natural ovulation. And only on the 3rd or even the 5th day it is fixed on the wall of the organ. It is during this short period of time that bleeding may occur. However, they have nothing to do with menstruation.
If the bleeding becomes abundant, then the woman is placed in the hospital for a full examination and preservation of pregnancy.
The reasons for this condition are as follows:
- Strong mental agitation. Usually this is facilitated by the IVF procedure itself.
- Violation of the prescribed bed rest after the procedure.
- Ectopic pregnancy.
- The development of erosions on the cervix.
- Aborted pregnancy.
- Increasing the thickness of the mucous membrane layer on the inner walls of the uterus.
- Hormonal imbalance, which occurred as a reaction of the ovaries to therapy.
- Inflammation of the pelvic organs.
Monthly after IVF occur in case of unsuccessful fertilization. This confirms the analysis of hCG. But do not get upset, rarely when the first IVF ends with pregnancy.
Monthly come on the 3-10th day after confirmation of unsuccessful conception.
Pretty quickly a woman's body normalizes the natural work of the monthly cycle. There are cases of loss of menstruation after an unsuccessful procedure. This is due to a strong hormonal disruption in the body of a woman. Often it becomes a consequence of a depressive state after failure. And we must not forget that the price of IVF is quite high and not everyone can afford 2 or even 3 procedures. The cost of the procedure starts from 90,000 rubles and can reach up to 300,000 rubles, depending on the region. Of course, an unsuccessful attempt causes a depressed woman.
Menstruation after IVF
Often women notice that menstruation changes after in vitro fertilization. Moreover, the nature of the discharge can be represented by several types:
- The blood is bright and rather liquid. No clots are observed. This is due to the large number of drugs taken by the woman over the past few months in preparation for the procedure.
- Monthly after IVF are accompanied by general malaise, pain in the lower back and abdomen. In this case, the state is normalized in 2-3 months.
- If after IVF menstruation with a large amount of blood and clots has gone, this is also normal, since in some cases the endometrium of the uterus is significantly enlarged. That is, the uterus was ready to accept the egg, but this time it did not work out.
- The delay of the first menstrual cycle after an unsuccessful procedure for 1 month or more indicates the appearance in the female reproductive system of cysts or polyps. This can confirm the examination of the fallopian tubes and uterus using ultrasound.
- The causes of menstruation after IVF are hormonal failure. If they can not normalize within 2-3 months, it is necessary to begin medical therapy. All the necessary drugs in this case are prescribed by the doctor.
When can IVF not work?
Successful IVF protocols are carefully studied in order to increase the percentage of conception using this procedure. Also, doctors carefully investigate all unsuccessful attempts to plant a fertilized cell for a woman. As scientists say: a negative result is also a result. That is, knowing the causes of failure will reduce the percentage of the latter.
Today, the following causes of failure are identified:
- Inflammatory processes in the female genital organs and urinary system.
- Age over 40 years.
- The lack of professionalism of the medical staff conducting the procedure.
- The endometrium layer is too thick on the walls of the uterus.
- Defective blastocysts.
- The impossibility of fertilizing the egg because of the genetic incompatibility of men and women.
- The presence in the blood of a woman traces of nicotine, alcohol, drugs.
- Diseases of the endocrine system.
- Excess weight.
What are the complications of the procedure?
IVF is in principle implemented successfully only in 35-40% of all cases. But there are also a number of complications arising during the procedure or after it.
- With an ectopic pregnancy, the risk of rupture of the fallopian tube is so high that it is removed surgically along with a fertilized egg.
- Syndrome of missed abortion. This phenomenon occurs in both natural fertilization and IVF. True, with artificial insemination is still more.
- With pregnancy overstimulation syndrome, the monthly cycle is disturbed. For subsequent recovery, a woman has to undergo hormone treatment.
What periods after unsuccessful IVF arise, the doctor will prompt after a full examination of the woman.
How to increase the chance of a successful conception using IVF?
No doctor, even if a woman is completely healthy, is not taken to guarantee the 100% chance of conception and the development of pregnancy. This is due to the huge number of different aspects.
What can be done to increase the chance for a favorable outcome of the procedure?
First of all, a woman needs to find the strength to calm down. To bring your psyche to a normal state, since stress and nervous tension is one of the reasons for failures during IVF. For sedation, you can take a mild antidepressant, but only one that the doctor prescribes. Self-administration of such drugs can worsen the situation.
Secondly, it is necessary to normalize your sleep pattern. After all, there are hormones in the body that are produced in a dream and only in the dark. That is, daytime sleep does not compensate a full rest.
Third, do not forget about healthy eating. No trendy diets and vegetarianism. A woman should eat varied and full. The body needs proteins from both animal and plant origin. Be sure to include in the diet of cereals, fresh fruits and vegetables. It is necessary to reduce the consumption of sweet, sweet pastry, it can increase the layer of subcutaneous fat. You can not drink sweet, carbonated drinks, for the same reason. It is necessary to completely eliminate from your diet fast food: fried potatoes, meat of dubious quality with preservatives and dyes. And most importantly - it is strictly forbidden to drink alcohol and smoke cigarettes.
Fourthly, you need to strengthen the body with regular exercise or at least daily walks.
When do I need to see a doctor?
Disruption of the regularity of the monthly cycle in most cases is not a problem, since it is caused by a slight malfunction of the endocrine system. Usually, cyclicity is restored independently with little effort on the part of the woman herself — adjusting sleep and diet, taking sedatives, and so on.
But there is a risk of developing dangerous pathologies, one of the manifestations of which is a failure in the cyclical nature of menstruation.
At the same time, a number of other symptoms appear, one can not but notice
- Lower abdominal pain. Painful, arising under load.
- Nausea sometimes with vomiting.
- A sharp, unwarranted increase in body weight.
- The skin of the face, hands and feet swells, especially in the morning.
You can not lightly relate to the fact that menstruation is complicated by such symptoms. This is fraught with the development of dangerous tumors in the female reproductive system.
Naturally, medical treatment is used to normalize the work of the entire female body, prepare it for the IVF procedure and restore it after an unsuccessful attempt to become pregnant. It is carried out only as prescribed by the doctor and exclusively under his supervision. Any attempt at self-treatment will necessarily worsen the situation.
Stimulation of ovulation is carried out with the following drugs: “Gonal”, “Klostilbegit”, “Menopur”, “Puregon”, “Pregnil” and others. Some of them are made in the form of capsules, others must be taken in the form of injections.
Most women, after an unsuccessful IVF procedure, need psychological help. The importance of such treatment should be understood. After all, when you try again, which could well be successful, it is the depressed, depressive state of a woman that can interfere with conception.
Only the help of a professional psychologist will help a woman to remove feelings of guilt and self-doubt. Do not underestimate the value of this method of therapy. Sometimes a few sessions with a psychotherapist are enough to improve a woman’s condition so that she becomes pregnant in a natural way.
In such a situation, the support of the spouse is very important. He must convince his woman that she is not guilty of failure. You can never give up.
Discharges after IVF can be a natural phenomenon, therefore, before you panic, you should visit a doctor and find out the reasons for this phenomenon. Anything can do. If it did not work out on the first attempt, then you need to do one more, and more, as much as is necessary to achieve success. The procedure ceases to be unique, it is used in all developed countries of the world, more and more clinics offer their services in artificial conception. All this affects the price per procedure - it is regularly reduced. Only a passionate desire to achieve a goal brings a positive result.
Causes of onset of menstruation
The causes of menstruation after IVF coincide with the reasons that prevent pregnancy.
- middle age of partners
- untreated inflammation of the female genital organs,
- defects in blastocysts (this is the early stage of embryo development),
- woman's dependence on drugs, alcohol or smoking
- insufficient thickness of the endometrium,
- genetic incompatibility of partners.
There may be one or several reasons, but the result is one - pregnancy that did not take place after IVF, and as a consequence, the restoration of the menstrual cycle.
In the case of successful IVF, there may also be a small discharge, similar to the beginning of menstruation.
The appearance of bleeding in case of successful transfer
The main and so long-awaited reason is implantation bleeding, while the discharge is small and ends quickly.
- Minor injuries to the vagina or cervix that occurred as a result of egg collection. Allocations are also insignificant and stop within a few days.
- If the pregnancy has begun, but an abundant bleeding, similar to the real menstrual period, accompanied by pain, it is necessary to urgently call an ambulance, these are symptoms of a beginning miscarriage.
If at the time of two weeks of waiting for the analysis for hCG there is a small bleeding, then it ends, then it starts, but there is no pain and discomfort, they are prescribed an analysis of the progesterone level, and also increase the dose of endometrial hormonal support in order to save the pregnancy, if it took place.
When to wait for critical days after a failed protocol?
Usually, After a negative analysis of hCG, menstruation occurs after 3–12 days. At the beginning of a small brown "daub" begins, which turns into a normal menstruation.
IVF is a serious blow to the hormonal system and the body of a woman, so the delay of menstruation after an unsuccessful procedure is quite natural. After some time, the hormonal system comes to its natural balance, but the timing of this is different for each woman.
It is necessary to react to a delay of monthly and understand that they will start sooner or later anyway. It is not necessary to indulge yourself with the thoughts that the pregnancy did come, but it was not recognized. Unfortunately, the analysis of hCG gives a 100% result. If he has shown that fertilization has not taken place, menstruation will definitely begin.
The reasons for the delay in the negative outcome of fertilization
The main reason is always stress and psychological stress. Many women become depressed after receiving a negative result for HCG. This shatters the hormonal system even more. Permanent nerves, tears do not allow the body to balance and begin to function normally.
There are cases when the first menstruation comes on time without significant delays, but further failures of the cycle appear. This is also quite common. The cycle after an unsuccessful IVF can recover from 3 to 6 months. In some cases, it may take a year to restore it.
In very rare cases, doctors cause monthly medication. This is permissible only under the supervision of physicians, self-administration of potent hormonal drugs is life threatening.
After an unsuccessful IVF, some women experience a pronounced premenstrual syndrome, which manifests itself in the form of nausea, dizziness, headache, pulling pain in the lower abdomen. Many are beginning to think that these are symptoms of a pregnancy that has begun. But before the analysis of hCG conclusions to do early.
You can not "prescribe" yourself any drugs to "support" pregnancy. This is a serious interference with the work of the endocrine system, which can lead both to the failure of the pregnancy (if it really was) and to an even longer delay in menstruation.
The first monthly ones after unsuccessful IVF will certainly be abundant. They can even go with clots. This is due to the fact that hormonal stimulation was carried out, causing endometrial thickening. Now the body must get rid of it, so heavy periods should not be surprising.
During superovulation, the endometrium connects with other layers of the uterus much more densely than with the normal one. This leads to the fact that the uterus during menstruation begins to contract much more, rejecting tissue that is unnecessary for the body, and clots may appear. Ultrasound at this time shows that the ovaries are increasing in size.
Availability of ICP
Even if its manifestation for a woman is uncharacteristically, after a failed IVF, almost everyone will face it. It manifests itself in the form of emotional lability, dizziness, bouts of nausea.
Premenstrual syndrome may appear a week before menstruation. It may be accompanied by a small brown "daubs", or it may be completely absent. Often women confuse it with toxicosis and hope that the pregnancy has come.
What to do to normalize the cycle and well-being?
Drugs are prescribed in the event that for three or more months the regularity of the monthly has not even approximately recovered, if they start randomly, then too early, then with huge delays. The doctor will send for an additional examination, as the reason for the fact that the cycle is not restored may be:
- latent chronic diseases of the female genital organs that have not previously been identified or were in remission.
The best thing a woman can do is:
- stop nervous and protect yourself from stress,
- to establish normal sleep and nutrition,
- light exercise, but not exhausting workouts will be helpful.
For any herbs, dietary supplements or vitamins, it is better to consult a doctor.
During critical days, it is all the more necessary to avoid stress and to realize that the psycho-emotional state is changing greatly. Therefore, it is impossible to take important decisions these days, find out relations with someone, quarrel. It is necessary to avoid in every way possible any conflicts and things that can spoil the mood.
Monthly after unsuccessful IVF is not a sentence, not a failure and not the end of life. Do not respond to this as a terrible tragedy. Remember that literally in every second case the first procedure is unsuccessful, therefore you should not grieve, it is better to prepare for the next one taking into account the experience you already have.
Что происходит после переноса?
After the transfer of fertilized eggs that have reached a certain age, measured in days after fertilization in the uterus, In a woman's body, events can develop in three scenarios:
- the embryo will take root, be able to penetrate the epithelium and continue to develop - the pregnancy will come,
- the ovum will take root, implant, but after a while it will be rejected by the mother's body or stop developing - the pregnancy will be interrupted at the earliest terms,
- the ovum fails to implant and dies - pregnancy will not come.
If the implantation is successful, the chorionic villi, which fetal membranes and attached to the wall of the uterus, will begin to produce a special substance - human chorionic gonadotropin, the concentration of which will increase approximately twice in blood and urine. If not one but two embryos take root, the content of this hormone will be exactly twice as high as the established norms.
Approximately two weeks after the transfer and successful implantation, HCG will begin to be determined in the blood plasma and in the urine. This will be the main diagnostic sign of a successful protocol - a woman can be congratulated on the occurrence of pregnancy.
If implantation does not occur - the growth of hCG is not observed, and if the pregnancy is interrupted, the concentration of chorionic gonadotropic hormone will be significantly below the norm.
With successful IVF and the onset of pregnancy, periods after the protocol should not begin. As with natural conception, the absence of menstruation is an indirect symptom of pregnancy. However, small bleeding after replanting may well be considered the norm.
First, they are associated with hormonal stimulation of superovulation, which was carried out in the first phase of the cycle prior to the collection of eggs, and secondly, they may be a sign of the hormonal support for the accompanying second phase of the cycle. Doctors recommend not to be nervous and calm down, if the discharge is not painful, not abundant, is not accompanied by other unpleasant symptoms and are in the nature of “smear”.
Within two weeks after the transfer of embryos into the uterine cavity of a woman, such secretions may well be the norm. You need to be wary in the event that bleeding increases, do not stop 14 days after transplantation, and also begin to be accompanied by pain.
First of all, the woman herself should be able to determine what the nature of the discharge is and whether they are similar to menstruation.
Types of discharge
A positive sign can be a selection that begins after three days from the time of embryo grafting. They can talk about the successful implantation of the latter into the endometrium of the uterus. Such bleeding is called implant bleeding. It is associated with a violation of the integrity of the endometrium at the time of the introduction into it of the ovum.
Implant bleeding can manifest as a few drops of blood on a daily pads or pinkish "daub." Highlight can also be brown or beige, but necessarily scanty. Abundant discharge during implantation should not be!
In addition to such secretions that cannot be considered monthly, during implantation, a woman may experience breast engorgement, increased sensitivity, a slight increase in body temperature, especially in the afternoon and evening, as well as increased irritability and emotional instability. There is usually no pain. Only sometimes women notice that they slightly pull and the stomach hurts, as before menstruation.
That is why implantation bleeding is often confused with the onset of menstruation. Unlike menstruation, implantation bleeding is not inclined to change the intensity, it does not become more abundant, the discharge does not contain clots and bright red blood. It usually lasts from several hours to several days and disappears before the date of the next menstruation.
It should be noted that implantation bleeding is not peculiar to everyone and does not always appear, therefore, it is not worth waiting for it. Quite often, implantation proceeds without pronounced symptoms, discharge and sensations.
Full menstruation after the "transit" IVF will not. Most often, the discharge is accompanied by a pulling pain in the lower abdomen, there are numerous blood clots in the discharge, but the menses themselves last a little less than usual - 3-4 days instead of 5-6 usual ones. Sometimes menstrual periods after unsuccessful IVF are longer than usual, but not more than 1-2 days.
Almost all women note that after a failed IVF attempt, menstruation is more painful than usual, the color of the discharge is more scarlet. These are the consequences of hormonal therapy; this will pass with subsequent menstruation. The onset of menstruation at a time appropriate for the cycle indicates the onset of menstrual bleeding, in which the uterus of a woman gets rid of dead ungraded embryos and excess endometrium, which was “increased” by hormones in the first half of the cycle.
The onset of bleeding after a delay, as well as a positive pregnancy test, may indicate a threatened miscarriage, a miscarriage that is starting or occurring. It is imperative to visit a doctor or call an ambulance to diagnose the disorder and, if possible, try to keep the pregnancy.
With successful implantation, discharge may begin due to a lack of progesterone, which should regulate the many processes of ensuring pregnancy in the early stages of the female body. For protocols with stimulation, supportive progesterone therapy after transplantation is usually prescribed. With protocols in the natural cycle, doctors try to do without drug support.
Sometimes this approach requires correction and the appointment of progesterone in certain doses from the very beginning of pregnancy up to 12-14 weeks, when the risk of miscarriage is considered less likely.
Causes of menstruation after the procedure
The reasons for which come monthly after in vitro fertilization, can be different - from violations of doctor's recommendations to inflammatory diseases, stress and even infection. When entering into the IVF protocol, a woman is usually warned that no one can guarantee pregnancy with a 100% probability. Provided that a woman is not 35 years old and her health condition does not cause anxiety at the doctor, the probability of pregnancy is estimated at 35-45%. This means that more than half of women after an IVF attempt will inevitably begin menstruation.
The probability of implantation and development of embryos decreases with the age of a woman: up to 35 years old - the chances are above 40%, after 40 years they fall to 8%. The cause of unsuccessful IVF can also be the effect of hormonal stimulation of the ovaries, which was necessary for the production of eggs.
Strong stress, which is exposed to a woman who is in the IVF protocol, is also not conducive to a successful beginning of pregnancy.
Embryos could be of insufficient quality, which prevented their implantation and development. The reason for the lack of implantation can be endometriosis, fibroids, hydrosalpinx (fluid accumulation in the fallopian tubes), as well as a rather impressive list of female diseases, which also prevents pregnancy.
Under the action of hormones, the woman's body is in shock. It may exacerbate chronic diseases, as well as infection with influenza, SARS or any other infection after embryo replanting. It is not at all necessary that the woman immediately starts to hurt badly, sometimes the symptoms of infections are quite obscure, but have a detrimental effect on the embryos.
Overweight, obesity women can also cause the arrival of menstruation after IVF. Sometimes the reason lies in the genetic incompatibility of partners.
Therefore, a genetics compatibility analysis is best done in advance, before joining the first protocol, since with such incompatibility, none of the attempts from these partners will succeed.
Experiences and stress, tears and excitement, quarrels with relatives after embryo replanting contribute to the production of stress hormones, which suppresses the production of progesterone, which is so necessary for the successful onset of pregnancy and its preservation. And bad habits (smoking, alcohol), if a woman cannot part with them after a replant in an IVF protocol, can reduce all the efforts of doctors.
Non-observance of medical recommendations is a reason rather rare, because women who went to IVF usually value the chance of pregnancy, because it is long-awaited and desirable for them. Sometimes violations occur unknowingly that steaming in a bath, going to a sauna, basking in a hot bath, loading yourself in a gym and having sex after replanting embryos is prohibited.
What to do?
If atypical bleeding occurs after IVF, you should definitely get a qualified medical consultation that will help establish whether it is menstruating or the risk of miscarriage.
If they came full monthly, pregnancy did not come, do not worry and despair. According to statistics, the second and third protocols are usually much more successful than the first. And some women in general have to postpone 8-9 attempts before they see the cherished two strips or positive blood test results for hCG.
In addition, there is a 25% chance that after an unsuccessful IVF attempt, pregnancy can occur in a completely natural way in bed, and not in a laboratory test tube. The fact is that hormonal therapy gives a powerful impetus to the female reproductive system.
If the cause of her infertility was not identified, endocrine, associated with violations of the cycle, it is the IVF protocol itself that can put everything in its place. Every fourth couple in such circumstances, it is possible to conceive a baby on their own after an unsuccessful attempt in the next 1-2 months.
If the cause of infertility is unremovable, you also do not need to despair. After the end of the month it is important to be examined, to find the cause of failure and to try again when the doctor allows.
About what a woman needs to know after embryo transfer, see the next video.
The first periods after IVF
After undergoing an IVF program, a test is usually done for HCG, that is, for the presence in the blood of human chorionic gonadotropin, a hormone that is produced by the female body only during pregnancy. A negative analysis shows that egg grafting was unsuccessful.
Within a week after the cancellation of hormonal drugs, and depending on the characteristics of the organism, the first menstrual periods should begin after embryo transfer. During this time, the body restores natural, hormonal processes, disturbed by the intake of the necessary, hormonal preparations. But there are cases when the arrival of menstruation is delayed.
Causes of delayed onset of menses
By itself, a small delay in the first menstruation, after failed fertilization, does not mean the presence of pathologies or an error in the hCG test, although often with a negative result, symptoms similar to early toxicosis appear, there is mild nausea, weakness, and pulling pain in the lower abdomen.
They mean only the body's natural response to hormonal stimulation. For advice, doctors should be consulted immediately only if the delay is more than ten days. There are several main reasons for the long absence of menstruation:
- in view of the individual characteristics, the body needs more time to restore its own hormonal background,
- unreasonable, contrary to the ban of doctors, hormonal preparations and vitamins for pregnant women, preventing the restoration of hormonal levels,
- forming, against the background of the procedure, luteal cysts and polyps,
- psychological stress, nervous breakdown after unsuccessful IVF and subsequent treatment.
Specific conclusions about the reasons for the delay will make the doctor according to the results of the examination of your body.
During the first menstruation
But now the time has come, and menstruation appeared. The first period after IVF - procedures may differ significantly from the usual and it is usually considered normal. Often, the first, after replanting, menstruation begins with minor bleeding, which later turns into a full menstruation.
This is a consequence of hormonal adjustment and is also considered the norm. The nature of the discharge also changes: they can be both painful and vice versa.
Menstrual flow is often more abundant with blood clots, as well as unusually long. The presence of blood clots in the menstrual flow is explained by the presence of pieces of the endometrium. Particles of the endometrium are also present in normal menstruation, but in this case, due to the increased hormonal levels, their presence is more tangible.
Against the background of a special psychological attitude, women sometimes take pieces of the endometrium or blood clots for embryos. This is not true, since even with successful fertilization, on such a short period of time, the embryo can be viewed only with a microscope.
Monthly after IVF
Often there are scanty periods after Eco. All again depends on the characteristics of the organism. Rarely enough, eco menstruation occurs in the form of bright, almost red blood, without any clots. They are nothing like menstrual. Such secretions are most likely the result of taking certain types of hormones. If such secretions are very abundant and their number does not decrease for some time, you should consult a doctor to exclude uterine bleeding. In any case, you need to understand that when the period began after the IVF procedure, they can not be the same as always. It is necessary, with understanding to treat your body and just go through the unpleasant sensations.
Irregular menstruation after IVF
Sometimes it happens that the first menstruation occurs on time, but then delays begin or, on the contrary, menstruation comes too often. In any case, you can not try to regulate the cycle independently, and especially with the help of hormonal drugs. This can lead to disruptions in the hormonal balance and lead to a worsening of the situation.
All hormonal preparations should be taken only after consulting a doctor. In any case, you can help your body cope with the situation with the help of natural remedies and recipes of traditional medicine, as well as strengthening the general condition of the body.
Check for menstruation after IVF
Special attention should be paid also to your psychological state. Excitement and prolonged stress as a result of waiting for the results of the replanting, as well as disappointment after an unsuccessful result, can cause depression.
In combination with the fact that the body is already in an not-quite-comfortable state, depression can cause long delays in the menstrual cycle.
Of course, the arrival of menstruation after an unsuccessful IVF and the body disorders following them are not entirely joyful. However, you need to try to accept and just survive the situation, not to self-medicate and follow all the doctor's prescriptions, and after a while the cycle normalizes. Full cycle recovery can occur over a period of three to six months, although in some particularly difficult cases it may take a year.
Video: Pregnancy after IVF: Inventions and Facts
The unusual course of the first menstruation after IVF does not give cause for concern, since it occurs under the influence of hormones. The fact that menstruation started after the fertilization procedure does not mean a recurrence of an unsuccessful situation with repeated IVF. Just before re-attempting artificial insemination, you need to take a short break, wait for the full recovery of the body. And your chances of success will increase significantly.
Monthly after a successful IVF procedure - what does it mean?
Sometimes in the first or second week, after the transfer of the blastocyst, a woman with despair watches herself smearing brown discharge with characteristic signs:
- small brown spots without admixture of red shades,
- discharge lasts no more than four days,
- after IVF, the stomach is pulling or sore, as during menses.
More often, such a “daub” after IVF occurs as a result of hormonal changes and is not a sign of failure. Often, doctors prescribe a drug like Gonal F to stimulate IVF.
In the process of implantation of an embryo, the zygote attaches to the endometrium of the uterus, and when deepening into the mucous membrane, slight damage to the capillaries can occur, resulting in a discharge of this nature.
Implantation can occur on the day of the proposed menstruation, and may be accompanied by various unpleasant symptoms.
Causes of possible bleeding
One of the main disadvantages of IVF is its low efficiency. Even among the best fertility specialists, the percentage of successfully completed protocols does not exceed 35–40%. Unsuccessful IVF is not a reason for panic.
Начавшаяся менструация в первые дни после ЭКО в 90% случаев является признаком:
Начавшаяся менструация в первые дни после ЭКО в 90% случаев является признаком:
В случае с выкидышем, месячные очень болезненны, что не характерно для несостоявшейся имплантации.
После экстренной консультации со специалистами могут быть выявлены и другие the causes of heavy discharge characteristic of complications after the use of assisted methods of artificial insemination:
- ovarian hyperstimulation (OHS),
OHS is manifested by increased blood clots, vascular permeability, blood secretions and the formation of effusion in the abdominal region.
Frequent complication after IVF in the presence of stored pipes with partial cross. With IVF, Decapeptyl can be used both during preparation and after transfer of embryos.
Moreover, due to the transfer of several embryos, implantation can occur simultaneously in both the uterus and the fallopian tube. More often such a violation ends with a missed abortion.
It is very difficult to diagnose a non-developing pregnancy in the early stages in the fallopian tubes. Indirectly, this can be indicated by the persistent for a long time scanty brown discharge after cleaning the uterus.
The increased size of the ovary due to hyperstimulation changes position on the leg. As a result of torsion, ovarian tissue can be trapped, followed by necrosis. The complication is also accompanied by severe pain, bleeding, and fever.
To limit the risks of complications after the completion of IVF, it is imperative that a woman complies with all the prescriptions and recommendations received in the clinic after the procedure. The IVF procedure can be free if you get a quota.
When to wait for monthly after unsuccessful IVF
It is important for women to see how long their periods start after an unsuccessful IVF. After the analysis of hCG or ultrasound showed no implantation or early missed abortion, discontinue treatment with crude. After discontinuation of the drug, menstruation should resume for a maximum of two weeks.
Prolonged absence of menstruation is caused by factors characteristic of patients after IVF:
Prolonged absence of menstruation is caused by factors characteristic of patients after IVF:
- Stress and depression from failure. Cortisol, produced by the adrenal glands with negative emotions, affects hormonal regulation.
- After stimulating treatment of the reproductive and endocrine system, time is needed to restore the natural mechanisms.
- Possible ectopic missed abortion does not allow the natural cycle to recover.
- Since the IVF protocol tries to achieve several simultaneously mature eggs, after puncture in the ovaries several yellow bodies are formed that carry the function of the luteal phase after the abolition of the drug progesterone support.
The later menstruation began after IVF transfer, the more difficult it is for the body to recover. Critical days then last longer and more abundantly.
If during the crescent after the unsuccessful IVF protocol and the cancellation of medications, the monthly delay continues, you need a doctor's advice. You may have to clean the uterus.
The second cycle (2 months) after IVF, as a rule, comes on schedule, as before the procedure of in vitro fertilization.
Possible changes in the menstrual cycle
After an unsuccessful attempt at conception, changes in the nature of menstruation can be noted:
- monthly after IVF abundant,
- Duration up to 12 days
- density due to the rejected thick uterine functional layer,
- after IVF, periods can be painful,
- general discomfort.
The menstrual cycle can change for a number of reasons:
The menstrual cycle can change for a number of reasons:
- During the protocol, reproductive and endocrine function was actively stimulated to achieve superovulation and further implantation.
- Many drugs taken after embryotransfer were directed to thickening of the walls of the endometrium and its tight attachment to the wall of the uterus, which is manifested by the release of dense mucous blood clots in the first cycle.
- To clear a dense endometrium, the uterus begins to contract very intensively, causing severe pain in a woman.
- After the abolition of luteal therapy, a sharp jump in the hormone estrogen occurs, provoking the profusion and duration of menstruation.
These changes in the cycle are short-lived and are considered as a variant of the norm. Vitamin-mineral complexes and sedatives may be corrected.
In the following menstrual cycles, menstrual periods come on time in an individual order for a woman.
Full recovery of the ovaries and endocrine system occurs after 3 months. After this period, repeated IVF attempts are possible. With each attempt, the chance of a successful outcome of the procedure increases.
Why IVF turned out to be unsuccessful, and what to do next, you can find out in the video:
Causes of menstruation after IVF
Girls who are familiar with the features of their own physiology know that the menstrual cycle ends monthly if fertilization of the egg during ovulation did not take place. During the IVF procedure, an artificially “manufactured” zygote (a cell resulting from the fusion of an egg cell and a spermatozoid) is inserted into a woman, after which it should be implanted into the endometrium. Then the body begins to release certain hormones that signal the onset of pregnancy and prevent the onset of menstruation. That is why the monthly after IVF may scare the girl, because their arrival means the failure of the procedure. But is it?
The reasons for menstruation after IVF may be only two:
- successful cell crouching
- unsuccessful cell crouching.
Successful cell crouching
At 6-8 days after IVF, the implantation of a fertilized egg into the uterine lining should occur. At this point, the zygote deepens and is fixed in the endometrium. At the same time, it can damage its capillary network, so spotting may occur that are not monthly! Such bleeding will be a signal of successful implantation of an egg cell, and the following features distinguish it from normal menstruation:
- insignificant amount of secretions that are smearing,
- the discharge is not dark red, but brownish,
- during implantation bleeding women should not experience pain in the lower abdomen,
- discharge does not last long (2-4 days).
If this is exactly the nature of bleeding, you can not worry about the failure of IVF, but still you should visit the doctor and pass the analysis for HCG, which will show for sure whether the implantation has occurred.
Failed cell crouching
Unfortunately, the extracorporeal method does not give a 100% chance that the woman should plant an egg cell successfully. The reason for this may be stress, instability of the hormonal background or diseases of the reproductive system, as well as other factors, so menstruation after IVF sometimes indicates a failed procedure.
After in vitro fertilization, a woman should regularly (every day or every few days) be tested for the hCG hormone. This active substance is partially excreted by the fertilized and implanted egg cell, and partly by the endometrium. It is necessary to maintain a constant level of progesterone, which stimulates the body to synthesize other pregnancy hormones, for example, prolactin.
HCG and progesterone inhibit the secretion of estrogen that can trigger menstruation and the risk of miscarriage.
The hCG index in case of successful implantation of the egg cell should increase every day, but if this does not happen, the woman suffered a failure after IVF, and she did not become pregnant.
When to wait for menstruation after an unsuccessful IVF
If the analysis for hCG showed no pregnancy, then progesterone maintenance therapy (it is sometimes used to contain sudden menses for 5–10 days after the fertilization procedure) stops, and the woman should wait for menstruation. The doctor can not say for sure when menstruation will come, but usually it happens from 3 to 15 days after unsuccessful IVF.
The nature of the first menstruation
Many women note that the first menstrual periods after IVF have an unusual character:
- more abundant
- last longer (8 to 12 days),
- endometrial clots in secretions significantly more than usual
- lower abdominal pain
- overall decline in well-being,
- nausea and dizziness.
The increase in menstrual flow is due to a sharp jump in estrogen after prolonged inhibition of its synthesis with progesterone therapy. A large number of clots are most often associated with the fact that supporting hormonal therapy provokes a significant thickening of the uterine mucosa for successful implantation.
In addition, discharge may be accompanied by severe lower abdominal pain, feeling unwell, weakness, nausea and dizziness.
The first periods after unsuccessful IVF have a similar character, because the woman's body during this procedure is experiencing severe hormonal stress. In a short period of time, the girl is injected with various active substances that will stimulate ovulation, implantation, restrain the release of estrogen and more. The endocrine system after this must restore its own work, and this takes time. Typically, the nature of menstruation normalized in a month.
Change in menstruation after IVF
Sometimes, after IVF menstruation changes its character, the possible effect is associated with severe stress that the endocrine system has experienced, which is why it cannot start working in a familiar rhythm for a while. Changes in menstruation can disturb a woman up to a year after an unsuccessful fertilization process is performed.
Long-term changes after IVF include the following:
- an increase in the profusion of menstruation,
- endometrial thickening,
- the appearance of severe pain.
With such symptoms, you need to contact your gynecologist to think about a future plan of action. When menstruation is of a very intense nature, a woman loses a lot of blood, so the doctor can prescribe her drugs containing iron and B vitamins, as well as fat-soluble A and E.
In addition, homeopathy can be used when drugs with plant hormone analogues will gently correct the endocrine system of a woman. Serious hormonal therapy is used only in extreme cases, because after a stressful IVF, it can worsen the condition of the reproductive system and harm the body.
Causes of delayed menstruation after IVF
Sometimes after IVF there is no monthly for a long time, but this is not associated with the onset of pregnancy. Menstruation may not start for a long period due to such reasons:
- severe stress after an unsuccessful procedure,
- the development of depression on the background of an unsuccessful IVF,
- long-term restoration of the reproductive system after hormonal therapy,
- ectopic pregnancy.
Strong emotional shock and depression increase the release of stress hormones by the adrenal cortex - cortisol, which adversely affects the work of many body systems, especially reproductive. A woman should understand that from the first time IVF may not work, and you should not be upset, because in the future it will entail health problems and significantly reduce success in subsequent attempts to get pregnant.
Sometimes hormone therapy is too “shock” for the body, so it can take up to a year to restore the normal menstrual cycle. In such cases, the woman should take all actions to normalize the reproductive system (they will be discussed below).
The last factor due to which menstruation does not begin is an ectopic pregnancy. Can I check it with tests? When ectopic implantation of the egg, hCG does not increase to the appropriate extent, since a significant part of this hormone is synthesized by the endometrium after implantation of the egg. Therefore, if the analysis of hCG showed no pregnancy, and monthly do not begin within 3-4 months, it is necessary to undergo an additional examination, including pelvic ultrasound and a blood test for hormones.
Irregular menstruation after IVF
After IVF, menstruation can go irregularly long enough - this is due to the slow recovery of the reproductive system. In this case, it is necessary to help the body to normalize the menstrual cycle using the following tools:
- herbal remedies with phytohormones,
- power supply,
- habits change
- correct exercise.
Phytopreparations can be prescribed only by a doctor. The most common preference is given to decoction of hop cones or boron uterus. In order for menstruation to begin normally, a woman should consume enough fat and protein, as well as vitamins and minerals. It is important to remember that alcohol, smoking, lack of sleep, the abuse of transfats can lead to disruptions in the endocrine and reproductive systems. From bad habits must be abandoned.
Shown sport. However, it is important not to overwork yourself and remember that during the recovery period after IVF, you can not make a big load on the abdominal muscles and lower back.
Over time, the menstrual cycle will normalize and become permanent, but until this happens, you need to regularly note when menstruation arrives and visit a gynecologist.
Monthly after the IVF procedure may come in case of failure when an egg is planted, or a woman will have slight bleeding, which often testifies to the success of the implantation. In any case, after fertilization, it is necessary to regularly monitor a gynecologist and follow his recommendations.
It is important to understand that after IVF menstruation can change its nature and regularity - this is due to intensive hormonal therapy. Over time, the state of the menstrual cycle and the reproductive system stabilizes.