The drug Norkolut is a drug used in gynecology.
The active substance of the drug is similar to hormones, it allows you to normalize the body during pregnancy, stabilize the endocrine system during menopause, delay the onset of menopause.
Often, lack of progestin can lead to infertility, irregularities in menstruation, inability to carry the child, early climax.
To avoid such problems, women are credited with a number of medications, including this drug.
Features of the composition
Doctors may prescribe this medicine as a contraceptive. It includes norethisterone, which provides a stable hormonal balance. Norkolut is available only in pills.
The drug gently affects the mucous membrane of the uterus, which helps to maintain it in the premenstrual state. The substance prevents the maturation of the egg, which allows the woman to normalize the menstrual cycle and hormones.
It is important to use the drug correctly so that there are no problems with violation of the cycle. The doctor will tell you in which dosage, and how long to use this medication.
In addition, it is recommended to take this medicine during a planned pregnancy. If you need to prepare the body for the upcoming infant and breastfeeding.
Norkolut is a natural stimulator of bust growth: it develops the mammary glands by increasing the glandular tissue and ducts.
Under the action of the components of the preparation, the breast is prepared for the production of milk.
Indications for use
This medicine has a wide spectrum of action and is used in gynecology for the treatment of such diseases and pathologies:
violation of the menstrual cycle, the absence of menstruation or the pain of their flow,
- development of premenstrual syndrome,
- diseases of the uterus (fibroids, the development of endometriosis, erosion on the neck),
- breast diseases,
- precancerous conditions (endometrial hyperplasia),
- as a contraceptive,
- to stop milk production,
- hypoplasia of the uterus (underdeveloped organ).
Methods of taking the drug
Depending on the type of the disease, Norkolut is taken in certain doses. To properly drink these pills, you need instructions for use. The drug is intended for oral use only.
It does not matter when to take the medicine: before or after meals, the main thing is to correctly calculate the dosage. Usually, how many pills to drink and how often - the doctor writes.
If it is necessary to treat premenstrual syndrome or menstrual disorders, the course of treatment is a week before menstruation (from 16 to 25 day of the cycle). Usually, it is prescribed in one or two tablets.
If it is necessary to treat diseases of the internal organs (uterus or ovaries), the course can last 6 months, but strictly from the 5th to the 25th day of the cycle. Take Norkolut with endometriosis pills for 10 days every month (during the year).
Instructions for use of the drug are significantly different when used as a contraceptive. To eliminate an unwanted pregnancy, it is necessary to take half a pill for three weeks at night.
After that, you need to pause for a week (for monthly periods). To increase the effectiveness of the drug, doctors recommend at the beginning of its use to combine with taking estrogen.
When pregnancy should be careful with respect to the use of this medication.
Norkolut tablets are prescribed to future mothers only if there is a serious threat - miscarriage.
Also, the drug is recommended to use after childbirth to eliminate lactation (with unwanted breastfeeding, or when the baby has already grown).
Contraindications and cautions
There are a number of absolute contraindications to the use of these pills:
- malignant tumors,
- allergic reaction to the drug.
Relative contraindications are the following factors:
liver and kidney problems
- overestimated bilirubin in the blood,
- thick blood with increased coagulability,
- epileptic seizures,
- diabetes and overweight,
Sometimes Norkolut can cause side effects: pain, nausea, vomiting and digestive problems. There may also be headache, allergies, itching, swelling.
In addition, during the use of the drug increases blood density, which is undesirable with weak blood vessels. If any symptoms appear, you should consult a specialist.
What can not drink these pills?
It is strictly forbidden to combine the drug with the following medicines: cimetidine, phenobarbital, rtfampicin, phenytoin. You should be careful when taking this substance in combination with steroid hormonal drugs and drugs that reduce blood clotting.
If you have a negative reaction of the body when using this medication, you need to talk to the gynecologist. The doctor will replace it with a good analogue.
Today, you can choose a suitable tool based on the needs of a woman: Utrozhestan can be taken to save pregnancy, but Klimaktol is considered a good analogue for menopause.
If you need to normalize hormones and eliminate uterine hypoplasia, the course Proginova will do.
As a means of contraception and the normalization of the menstrual cycle - Diane-35.
Postinor, Pregnin and the like are also considered good analogues. Such drugs are complex and do well with hormonal problems. Also for normalization of the endocrine system use Orgametril, Escapel, Primolut-Nor.
The composition and action of the drug
The active ingredient in Norkolut is norethisterone.
Norkolut's action is aimed at maintaining the secretory state of the uterine lining. Taking the drug provides blocking of individual hormones of the pituitary gland and does not allow for the maturation of a new egg when it leaves the ovary.
Indications for the appointment of the drug
The reason for treatment with a drug may be the following pathological conditions:
- the presence of endometriosis,
- lack of ovulation
- diseases of the mammary glands,
- delay of menstruation,
- pathology of the uterus.
Reception Norkolut carried out if necessary, termination of pregnancy and cessation of lactation. It is also used as a contraceptive drug and during menopause to eliminate the negative manifestations of the body. Norkolut is used in the presence of premenstrual syndrome and painful flow of menstruation.
Tablets are used inside and washed down with a sufficient amount of water. The meal time does not affect the effect of the drug. Dosage for various pathologies is individual.
During menstruation, Norcolut is discontinued because The drug contributes to a significant increase in the volume of blood discharge, increased pain and the development of pathological changes in the uterine mucosa.
Not recommended drinking alcohol during the course of treatment. If you still have to take alcohol, then you should not forget that between the intake of Norkolut and the use of alcoholic drink should take more than 3-4 hours. The greatest danger is alcohol for the liver, which in such cases is difficult to cope with the load.
Before taking the drug is recommended to be examined to eliminate contraindications to such treatment.
In what cases you can not use the medicine
Attention should be paid to contraindications to therapy with a drug. In accordance with the instructions for use Norkolut not allowed for treatment for the following health problems:
- elevated levels of bilirubin in the blood,
- acute and chronic liver pathologies,
- malignant tumors,
- the presence of herpes,
- any bleeding of unknown origin,
- individual intolerance to the components of the drug,
- bronchial asthma,
- inflammatory pathology of veins.
Be careful with taking the drug if there are such diseases:
- functional kidney failure,
- endocrine system pathologies,
- heart failure,
- malfunction of the central nervous system.
Hormone remedy is not recommended for children under 18 years old, pregnant women and during the planning period of conception.
Before taking the drug should consult a doctor to avoid unwanted complications that pose a health hazard.
Possible side effects
With the passage of a course of drug therapy, side effects sometimes occur. Taking Norkolut often causes disorders of the digestive process, manifested by nausea and vomiting, diarrhea and constipation.
There are other negative phenomena:
- blood pressure surges,
- allergic rashes on the skin,
- increased hair growth
- weight gain
- swelling of limbs
- violation of the blood,
- vision problems
- excess fat on the skin.
During the course of treatment, the mammary glands often become coarser and nipple sensitivity increases.
Taking the drug can cause malfunction of the nervous system, accompanied by headaches, decreased sensitivity of the extremities, decreased performance and the development of fatigue.
The use of drugs to remove menstruation
How to apply Norkolut to delay menstruation - a specialist will advise. Selecting the necessary treatment regimen, the doctor takes into account both the individual characteristics of the body and the presence of certain chronic diseases. Thanks to norethisterone, a thick layer of the endometrium is rejected later and there is a delay in menstruation.
To get a positive result, the drug is started up 1 week before the onset of menstruation. The recommended dosage is 2 tablets per day. The duration of therapy is 12 days.
This treatment regimen allows you to postpone critical days for one to one and a half weeks.
Reception and cancellation Norkolut held under the supervision of a specialist.
Application for delayed menstruation
If menstruation is absent for a long period, they are treated with a medication for 5-10 days. After the cancellation of Norkolut, the monthly periods begin within a week. But the drug should be taken only after the examination, because delayed menstruation can be caused by conception.
Norkolut during pregnancy and lactation
The active component in the composition of the drug contributes to the termination of lactation. Taking the drug reduces the production of milk in the mammary glands. Norcolut is used if breastfeeding is not recommended for any reason.
The course of treatment is 10 days. Therapy is carried out in several stages. In the first 3 days, take a pill 4 times a day. Then the daily dosage is reduced to 3 tablets and they are drunk for another 4 days. In the last period of treatment, they switch to taking the drug in the amount of 2 tablets per day.
Norkolut is used and if necessary, to prevent lactation, if there is a premature birth.
Begin the use of the drug with 5 days after the start of menstruation. Use half a tablet at bedtime for 21 days. Then make a seven-day pause and again resume the use of the drug. At the beginning of treatment, estrogen is also taken, which is chosen individually by the attending physician.
During the reception
Under the influence of the active substance, there is a natural blood flow, the amount of which decreases by the end of the cycle. Menstruation is scanty and ends in a short time. Such its course is the norm and should not cause concern for women.
Sometimes there are individual reactions of the body, which are manifested by nausea, vomiting, increased pain and swelling of the limbs. After the cancellation of Norkolut, the cycle is normalized.
In most cases, the usual nature of menstruation does not change. Sometimes the discharge is very small. This is facilitated by an increase in blood clotting resulting from the action of the drug.
Rarely there is abundant bleeding, which requires skilled care. Gynecologists attribute this condition to the side effects of the drug.
Blood discharge may be darker in color, and the duration of menstruation is reduced. This condition after taking Norkolut often persists for several months. Then the usual schedule is restored.
Rarely there are cases when after the end of treatment the periods do not occur. With this option, you should consult your doctor to exclude pregnancy and adjust the treatment regimen.
The simultaneous intake of hepatic enzyme inducers leads to an increase in the action of norethisterone. With caution they take the drug in combination with other hormonal drugs and drugs that affect blood clotting and sugar concentration in it.
Also not recommended for parallel use:
Analogues of Norkolut
With therapy aimed at postponement of menstruation, you can use other pharmacological agents that are similar in their composition or effect on the body.
To exclude unwanted complications when choosing a drug, you should carefully study the instructions and focus on the individual tolerance of a particular drug.
Patients note that the medicine is effective in normalizing the menstrual cycle, in order to distance or approach menstruation. Pay attention to its affordability, but at the same time indicate a large number of side effects from the body. Here are some reviews about the drug that we borrowed.
Christina, 28, Omsk.
Used Norkolut before the release, because I wanted to postpone menstruation. It turned out to postpone the critical days by only 5 days. But I want to draw attention to the fact that the monthly flowed harder than usual. The discharge was profuse, and was disturbed by severe pain.
Svetlana, 31, Murmansk.
When there were problems with the menstrual cycle, I decided to consult a gynecologist. I was prescribed Norkolut for the normalization of menses. She underwent therapy for 3 months. She took the medicine well, did not observe any side effects. I am glad that everything has returned to normal, for more than a year the cycle has remained regular.
Maria, 42, Kolomna.
Norkolut really helps delay menstruation. Began to take the drug for 6 days before the start of the cycle. Saw 1 tablet at 7 am and before bedtime. After cessation of treatment, menstruation occurred after 4 days. But do not forget that this is a hormonal agent. It can produce dangerous complications, and there are numerous contraindications to its use. It is better to consult a gynecologist in advance so as not to harm health.
Indications for use
A hormonal agent is designed to eliminate:
- Menstruation cycle failure, which is accompanied by a reduction in the secretory phase
- Mastodynias (pain in the mammary glands)
- Uterine bleeding with menopause
- Endometrial Tissue Hyperplasia
- Adenomyosis of the uterus.
Also, the drug helps suppress and prevent lactation.
The therapeutic effect of Norkolut is achieved thanks to its active ingredient - norethisterone. The substance belongs to the group of gestagens, but, despite this, it has the qualities of androgens and extragens, although to a lesser extent. After penetration into the body contributes to the restructuring of the uterus, activating secretory changes in the endometrium, prevents the production of gonadotropin in the brain, stops the maturation of the follicles and the process of ovulation.
After oral administration, the drug is easily absorbed from the gastrointestinal tract. The highest levels of content are achieved within 1-2 hours. Converted in the liver, after the first stage of transformation, its bioavailability is approximately 50-76%. The withdrawal from the body is carried out in two stages, the half-life is first about 2.5 hours, in the final stage -
8. A significant part of the derived substances is excreted by the urine - almost 70%, the rest is excreted by feces.
Forms of release
Average price: (20 pcs.) - 110 rubles.
The drug is produced in tablets - white or whitish pills with beveled edges and markings on both sides. On one surface, the name of the drug in Latin (NORCOLUT) is superseded, on the other - there is a sign in the form of a cross (plus sign). The tool is packaged in blisters of 10 pieces. In a pack with instructions for use - 2 blisters.
Norkolut with endometriosis
Therapy begins between the first and fifth day of the cycle. It is recommended to drink twice a day, 1 tablet. In the case of bloody discharge, the dosage is increased to 2 pills at a time (total - 4 pcs.). After stopping the discharge returns to the initial amount. The duration of therapy is at least 4-6 months. With daily admission without interruption, menstruation and ovulation do not occur. After completion of therapy with Norkolut, withdrawal bleeding occurs.
Drug as a contraceptive
Norkolut can be used to prevent unwanted pregnancy. To do this, it must begin to take on day 5 of the cycle. The tablets are drunk for the night (1 / 4-1 / 2 pcs.) For a 3-week course, after which they make a week pause and then resume their intake. In the first weeks of taking the doctor may additionally prescribe estrogen.
Norcolut to delay monthly
To shift the beginning of the menstrual cycle, tablets should be drunk 8 days before the expected day of menstruation. The tool is taken daily for 12 days, drinking 2 pills at a time. It is believed that with this order, the onset of menstruation will move for a week. However, it must be borne in mind that the forced regulation of the natural process may affect the nature of the bleeding: copious periods after Norkolut are not excluded.
How to cause monthly
Before taking you should make sure that the violation of the cycle is not associated with pregnancy. To cause menstruation during its delay, the tablets are drunk 2 pieces per day for 5 days. Abrupt termination of the course causes bleeding. This method can not be used without the consent of the doctor, as each patient has its own characteristics that can cause unexpected reactions.
During pregnancy and HB
The drug is not intended for the treatment of pregnant women. Although there are cases when women who were unaware of their situation took Norcolut pills, and after giving birth to healthy babies. However, this cannot be considered a regularity, since no one conducted special studies on the effects of Norkolut on the development of the fetus. Therefore, admission can be allowed only in extreme cases - if there is a threat of termination of pregnancy.
Nursing women are prescribed drugs if there are difficulties in weaning a child. It is known that Norkolut in the postpartum period reduces the production of milk and changes its characteristics. It is also prescribed to suppress milk production for women who have miscarried for various reasons.
Norkolut is prohibited for use if the patient has at least one of the following factors:
- Individual response of the body to the components of drugs
- Puberty period
- Breast cancer (diagnosed and suspected)
- Malignant neoplasms of the female organs
- Pregnancy (use is possible as an exception if threatened with miscarriage)
- Jaundice (available either in history)
- Acute liver pathologies
- Neoplasms of the liver of any kind
- Liver / Kidney Dysfunctions
- Predisposition to thrombosis
- Thrombophlebitis / acute embolism
- Urogenital system: bleeding of unknown origin
- Cholestatic hepatosis pregnant
- Itchy skin (in history)
- Herpetic infection.
Medication can be administered with precautions if the patient has: diabetes, asthma, chronic heart disease, epilepsy, hypertension, frequent migraines. In the case of prescribing drugs, the therapy should be under medical supervision.
If at the time of taking Norkolut, atypical states have appeared, the state of health has worsened, it is necessary to inform the attending doctor immediately.
Before initiating therapy with a hormonal agent, it is necessary to make sure that there are no malignant tumors, to conduct a series of examinations (gynecological, oncological), to check the condition of the mammary glands.
If you miss the pill, it should be taken at the earliest opportunity, and resort to additional contraception.
It has been established that some medications can reduce the effectiveness of Norkolut. Such drugs are drugs that increase its metabolism - antiepileptic (phenytoin, oxcarbazepine, barbiturates, etc.), anti-tuberculosis (rifampicin), as well as some antibiotics and herbal medicine with hunters.
Norkolut can distort the effect of drugs with cyclosporine when used together.
In order to avoid unpredictable reactions, the treating physician should be informed about all medications that were taken at the time of prescribing Norkolut or in the previous period.
Reception Norkolut can be accompanied by numerous undesirable phenomena. Impairment of well-being provoke violations in the work of internal organs and systems:
- The manifestation of individual allergic reactions
- Headaches, migraines
- Blurred vision
- Nausea, vomiting
- Rash, urticaria
- Bleeding from the uterus or vagina
- Violation of menstruation (scarce bleeding, amenorrhea)
- Severe irritability, aggressiveness, fatigue
- Swelling of tissues
- The occurrence of thromboembolism, thrombophlebitis
- Liver neoplasms leading to internal bleeding
- Heavy chest
- The occurrence of hepatitis
- A strong increase in blood pressure.
Prolonged use of Norkolut in large doses often provokes cholestasis.
Terms and conditions of storage
The drug is usable for 5 years. Keep in a place away from sunlight, at t ° from 15 to 30 ° C.
Replace Norkolut identical means can only the treating physician.
"Deco", "Farm-Sintez" (RF)
Cost: spray (17.5 ml) - 636 rubles.
Hormonal agent for use in gynecology. Used for the treatment of endometriosis, uterine fibroids, endometrial pathologies, elimination of infertility (used for IVF). Buserelin stimulates a short-term increase in the content of sex hormones in plasma.
Medication contains buserelin - a substance created by artificial means. It has properties similar to natural GnRH.
It is produced as a nasal spray. A single dose (1 injection) contains 150 mcg of buserelin. The daily amount is divided into several stages and injected into the nose with equal time intervals.
Buserelin can not be used in pregnant and lactating women, individuals with individual hypersensitivity. Special care should be exercised during therapy if the patient is diagnosed with hypertension, diabetes, and depression.